At the BID lab, we are mainly focusing on:
– Biogenesis of S. pneumoniae EVs
We explore how EVs are formed under various environmental stimuli, such as an infection scenario or varying nutrient availability. Using molecular biology, biochemistry, and super-resolution microscopy, we aim to reveal the molecular machinery driving vesicle production and their role in bacterial survival and adaptation.
– Biological Processes & Metabolic Cost of EVs Formation
Our lab employs advanced single-cell and single-molecule techniques to understand how S. pneumoniae allocates resources for EVs formation. We investigate the metabolic cost of this process and its effect on key cellular mechanisms, such as protein allocation to the cell wall.
– Host-Pathogen Interactions & EV Dynamics
Leveraging confocal microscopy and infection models, we study how S. pneumoniae interacts with host cells. We look at how EVs mediate these interactions, facilitating immune evasion, modulating the host response and how does the bacterial surface architecture dynamically rearranges.
Bacterial Interface Dynamics (BID) - Vilhena lab
Conferences, Exhibitions, Workshops & Podcast
In this section, you can find info on attended conferences, online talks, workshops and everything about my involvement in science outreach.
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